Linagliptin (GSK2118436)
Product Specifications
CAS Number
668270-12-0
Synonyms
BI-1356
Target
Ferroptosis
Applications
Apoptosis
Smiles
CC#CCN1C2=C (N=C1N3CCCC (C3) N) N (C (=O) N (C2=O) CC4=NC5=CC=CC=C5C (=N4) C) C
Molecular Formula
C25H28N8O2
Additionnal Information
Linagliptin (GSK2118436) is a highly potent, selective DPP-4 inhibitor with IC50 of 1 nM and exhibits a 10,000-fold higher selectivity for DPP-4 than for other dipeptidyl peptidases such as DPP-2, DPP-8, and DPP-9. Linagliptin activates glomerular autophagy in a model of type 2 diabetes. DPP4 mediates ferroptosis in TP53-deficient CRC cells.
Storage Conditions
2 years -80 in solvent
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS7191992 Inquire
Rabbit anti-Escherichia coli (strain UTI89/UPEC) YEAL Polyclonal Antibody
Sign In for Pricing
View Details 59093141 1x 10^6 Cells / 1.0 mL
HMG1P CRISPR Knock Out 293T Cell Line (Human)
Sign In for Pricing
View Details abx532083 96 Tests
Mouse Transcription factor MafB (MAFB) ELISA Kit
Sign In for Pricing
View Details