Linagliptin (GSK2118436)
Product Specifications
CAS Number
668270-12-0
Synonyms
BI-1356
Target
Ferroptosis
Applications
Apoptosis
Smiles
CC#CCN1C2=C (N=C1N3CCCC (C3) N) N (C (=O) N (C2=O) CC4=NC5=CC=CC=C5C (=N4) C) C
Molecular Formula
C25H28N8O2
Additionnal Information
Linagliptin (GSK2118436) is a highly potent, selective DPP-4 inhibitor with IC50 of 1 nM and exhibits a 10,000-fold higher selectivity for DPP-4 than for other dipeptidyl peptidases such as DPP-2, DPP-8, and DPP-9. Linagliptin activates glomerular autophagy in a model of type 2 diabetes. DPP4 mediates ferroptosis in TP53-deficient CRC cells.
Storage Conditions
2 years -80 in solvent
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS2612065-01 48 Well
Rat purkinje cell autoantibody (PCA-1/Yo) ELISA Kit
Sign In for Pricing
View Details MBS2612065-02 96 Well
Rat purkinje cell autoantibody (PCA-1/Yo) ELISA Kit
Sign In for Pricing
View Details MBS2612065-03 5x 96 Well
Rat purkinje cell autoantibody (PCA-1/Yo) ELISA Kit
Sign In for Pricing
View Details MBS2612065-04 10x 96 Well
Rat purkinje cell autoantibody (PCA-1/Yo) ELISA Kit
Sign In for Pricing
View Details 
LV727096 1.0 µg DNA
GRPEL2P1 Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)
Sign In for Pricing
View Details MBS6290039-01 0.1 mL
CUGBP2, CT (CELF2, BRUNOL3, CUGBP2, ETR3, NAPOR, CUGBP Elav-like family member 2, Bruno-like protein 3, CUG triplet repeat RNA-binding protein 2, CUG-BP-and ETR-3-like factor 2, ELAV-type RNA-binding protein 3, Neuroblastoma apoptosis-related RNA-binding
Sign In for Pricing
View Details