Niclosamide
Product Specifications
CAS Number
50-65-7
Synonyms
BAY2353, Niclocide, NSC 178296
Target
STAT
Applications
Apoptosis
Smiles
C1=CC (=C (C=C1[N+] (=O) [O-]) Cl) NC (=O) C2=C (C=CC (=C2) Cl) O
Molecular Formula
C13H8Cl2N2O4
Additionnal Information
Niclosamide can inhibit DNA replication and inhibit STAT3 with IC50 of 0.7 μM in a cell-free assay. Niclosamide selectively inhibited the phosphorylation of STAT3 and had no obvious inhibition against the activation of other homologues (e.g., STAT1 and STAT5) .
Storage Conditions
2 years -80 in solvent
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