Cabazitaxel

Product Specifications

CAS Number

183133-96-2

Synonyms

XRP6258, RPR-116258A, TXD 258, Taxoid XRP6258

Target

Microtubule Associated

Applications

Cytoskeletal Signaling

Smiles

CC1=C2C (C (=O) C3 (C (CC4C (C3C (C (C2 (C) C) (CC1OC (=O) C (C (C5=CC=CC=C5) NC (=O) OC (C) (C) C) O) O) OC (=O) C6=CC=CC=C6) (CO4) OC (=O) C) OC) C) OC

Molecular Formula

C45H57NO14

Additionnal Information

Cabazitaxel is a semi-synthetic derivative of a natural taxoid that kills cancer cells by inhibiting cell division and growth. Cabazitaxel exerts its effects by inhibiting microtubule growth and assembly, processes that are essential for cells to divide. Cabazitaxel induces autophagy via the PI3K/Akt/mTOR pathway.