CU-T12-9
Product Specifications
CAS Number
1821387-73-8
Target
TLR
Applications
Immunology & Inflammation
Smiles
CNC1=C (C=C (C=C1) [N+] ([O-]) =O) [N]2C=NC (=C2) C3=CC=C (C=C3) C (F) (F) F
Molecular Formula
C17H13F3N4O2
Additionnal Information
CU-T12-9 is a specific agonist of Toll-like receptor (TLR) 1/2 with EC50 of 52.9 nM in HEK-Blue hTLR2 SEAP assay. CU-T12-9 activates both the innate and the adaptive immune systems. CU-T12-9 signals through NF-κB and invokes an elevation of the downstream effectors TNF-α, IL-10, and iNOS.
Storage Conditions
3 years -20°C powder
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