Dooku1
Product Specifications
CAS Number
2253744-54-4
Target
Mechanosensitive Channel
Applications
Transmembrane Transporters
Smiles
ClC1=C (CSC2=NN=C (O2) C3=CC=C[NH]3) C (=CC=C1) Cl
Molecular Formula
C13H9Cl2N3OS
Additionnal Information
Dooku1 is an analog of Yoda1 with antagonist activity against mechanosensitive Piezo1 channel. Dooku1 inhibits 2 μM Yoda1-induced Ca2+-entry with IC50 of 1.3 μM in HEK 293 cells and 1.5 μM in HUVECs, respectively.
Storage Conditions
3 years -20°C powder
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