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BAY 11-7082

Product Specifications

CAS Number

19542-67-7

Synonyms

BAY 11-7821

Target

Apoptosis related

Applications

Apoptosis

Smiles

CC1=CC=C (C=C1) S (=O) (=O) C=CC#N

Molecular Formula

C10H9NO2S

Additionnal Information

BAY 11-7082 (BAY 11-7821) is a NF-κB inhibitor, inhibits TNFα-induced IκBα phosphorylation with IC50 of 10 μM in tumor cells. BAY 11-7082 inhibits ubiquitin-specific protease USP7 and USP21 with IC50 of 0.19 μM and 0.96 μM, respectively. BAY 11-7082 induces apoptosis and S phase arrest in gastric cancer cells.

Storage Conditions

2 years -80 in solvent

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