S-Ruxolitinib (INCB018424)
Product Specifications
CAS Number
941685-37-6
Target
JAK
Applications
Angiogenesis
Smiles
C1CCC (C1) C (CC#N) N2C=C (C=N2) C3=C4C=CNC4=NC=N3
Molecular Formula
C17H18N6
Additionnal Information
S-Ruxolitinib is the chirality of INCB018424, which is the first potent, selective, JAK1/2 inhibitor to enter the clinic with IC50 of 3.3 nM/2.8 nM, >130-fold selectivity for JAK1/2 versus JAK3. Phase 3.
Storage Conditions
2 years -80 in solvent
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