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GW441756

Product Specifications

CAS Number

504433-23-2

Target

Trk receptor

Applications

Protein Tyrosine Kinase

Smiles

CN1C=C (C2=CC=CC=C21) C=C3C4=C (C=CC=N4) NC3=O

Molecular Formula

C17H13N3O

Additionnal Information

GW441756 is a potent, selective inhibitor of TrkA with IC50 of 2 nM, with very little activity to c-Raf1 and CDK2. GW441756 produces a relevant increase of caspase-3 that leads to apoptosis.

Storage Conditions

2 years -80 in solvent

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