GW5074
Product Specifications
CAS Number
220904-83-6
Target
Raf
Applications
MAPK
Smiles
C1=CC2=C (C=C1I) C (=CC3=CC (=C (C (=C3) Br) O) Br) C (=O) N2
Molecular Formula
C15H8Br2INO2
Additionnal Information
GW5074 is a potent and selective c-Raf inhibitor with IC50 of 9 nM, no effect on the activities of JNK1/2/3, MEK1, MKK6/7, CDK1/2, c-Src, p38 MAP, VEGFR2 or c-Fms is noted. GW5074 inhibits LK-induced apoptosis.
Storage Conditions
2 years -80 in solvent
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