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T0070907

Product Specifications

CAS Number

313516-66-4

Target

PPAR

Applications

DNA Damage/DNA Repair

Smiles

C1=CC (=C (C=C1[N+] (=O) [O-]) C (=O) NC2=CC=NC=C2) Cl

Molecular Formula

C12H8ClN3O3

Additionnal Information

T0070907 is a potent inhibitor of PPARγ (peroxisome proliferator activator receptor γ) that induces G2/M arrest and enhances the effect of radiation in human cervical cancer cells through mitotic catastrophe. It also acts as an antagonist of PPARγ that suppresses breast cancer cell proliferation and motility via both PPARgamma-dependent and -independent mechanisms.

Storage Conditions

2 years -80 in solvent

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