SAR131675
Product Specifications
CAS Number
1433953-83-3
Target
VEGFR
Applications
Protein Tyrosine Kinase
Smiles
CCN1C (=C (C (=O) C2=C1N=C (C=C2) C#CC (C) (COC) O) C (=O) NC) N
Molecular Formula
C18H22N4O4
Additionnal Information
SAR131675 is a VEGFR3 inhibitor with IC50/Ki of 23 nM/12 nM in cell-free assays, about 50- and 10-fold more selective for VEGFR3 than VEGFR1/2, little activity against Akt1, CDKs, PLK1, EGFR, IGF-1R, c-Met, Flt2 etc.
Storage Conditions
2 years -80 in solvent
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