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Tideglusib

Product Specifications

CAS Number

865854-05-3

Synonyms

NP031112, NP-12

Target

GSK-3

Applications

PI3K/Akt/mTOR

Smiles

C1=CC=C (C=C1) CN2C (=O) N (SC2=O) C3=CC=CC4=CC=CC=C43

Molecular Formula

C19H14N2O2S

Additionnal Information

Tideglusib is an irreversible, non ATP-competitive GSK-3β inhibitor with IC50 of 60 nM in a cell-free assay; fails to inhibit kinases with a Cys homologous to Cys-199 located in the active site. Phase 2.

Storage Conditions

2 years -80 in solvent

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