Tideglusib
Product Specifications
CAS Number
865854-05-3
Synonyms
NP031112, NP-12
Target
GSK-3
Applications
PI3K/Akt/mTOR
Smiles
C1=CC=C (C=C1) CN2C (=O) N (SC2=O) C3=CC=CC4=CC=CC=C43
Molecular Formula
C19H14N2O2S
Additionnal Information
Tideglusib is an irreversible, non ATP-competitive GSK-3β inhibitor with IC50 of 60 nM in a cell-free assay; fails to inhibit kinases with a Cys homologous to Cys-199 located in the active site. Phase 2.
Storage Conditions
2 years -80 in solvent
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