Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Torin 2

Product Specifications

CAS Number

1223001-51-1

Target

ATM/ATR

Applications

PI3K/Akt/mTOR

Smiles

C1=CC (=CC (=C1) N2C (=O) C=CC3=CN=C4C=CC (=CC4=C32) C5=CN=C (C=C5) N) C (F) (F) F

Molecular Formula

C24H15F3N4O

Additionnal Information

Torin 2 is a potent and selective mTOR inhibitor with IC50 of 0.25 nM in p53−/− MEFs cell line; 800-fold greater selectivity for mTOR than PI3K and improved pharmacokinetic properties. Inhibition of ATM/ATR/DNA-PK with EC50 of 28 nM/35 nM/118 nM, in PC3 cell lines respectively. Torin 2 decreases cell viability and induces autophagy and apoptosis.

Storage Conditions

2 years -80 in solvent

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

DEAE Cellulose 11 analytical grade for molecular biology
47478-01 5 g

DEAE Cellulose 11 analytical grade for molecular biology

Sign In for Pricing
View Details
DEAE Cellulose 11 analytical grade for molecular biology
47478-02 25 g

DEAE Cellulose 11 analytical grade for molecular biology

Sign In for Pricing
View Details
Anti-IL-20 Antibody (Cheng Kung U. patent anti-IL-20)
F2010-.1 100 µg

Anti-IL-20 Antibody (Cheng Kung U. patent anti-IL-20)

Sign In for Pricing
View Details
Rabbit Anti-Pig IgG H&L Antibody (AF750)
abx142656-01 100 µL

Rabbit Anti-Pig IgG H&L Antibody (AF750)

Sign In for Pricing
View Details
Rabbit Anti-Pig IgG H&L Antibody (AF750)
abx142656-02 500 µL

Rabbit Anti-Pig IgG H&L Antibody (AF750)

Sign In for Pricing
View Details
Rabbit Anti-Pig IgG H&L Antibody (AF750)
abx142656-03 1 mL

Rabbit Anti-Pig IgG H&L Antibody (AF750)

Sign In for Pricing
View Details