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Ipatasertib (GDC-0068)

Product Specifications

CAS Number

1001264-89-6

Synonyms

RG7440

Target

Akt

Applications

PI3K/Akt/mTOR

Smiles

CC1CC (C2=C1C (=NC=N2) N3CCN (CC3) C (=O) C (CNC (C) C) C4=CC=C (C=C4) Cl) O

Molecular Formula

C24H32ClN5O2

Additionnal Information

Ipatasertib (GDC-0068, RG7440) is a highly selective pan-Akt inhibitor targeting Akt1/2/3 with IC50 of 5 nM/18 nM/8 nM in cell-free assays, 620-fold selectivity over PKA. Phase 2.

Storage Conditions

2 years -80 in solvent

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