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Daporinad (FK866)

Product Specifications

CAS Number

658084-64-1

Synonyms

APO866

Target

Transferase

Applications

Metabolism

Smiles

C1CN (CCC1CCCCNC (=O) C=CC2=CN=CC=C2) C (=O) C3=CC=CC=C3

Molecular Formula

C24H29N3O2

Additionnal Information

Daporinad (FK866) effectively inhibits nicotinamide phosphoribosyltransferase (NMPRTase; Nampt) with IC50 of 0.09 nM in a cell-free assay. Daporinad (FK866, APO866) triggers autophagy. Phase 1/2.

Storage Conditions

2 years -80 in solvent

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