Lonafarnib (SCH66336)
Product Specifications
CAS Number
193275-84-2
Target
Transferase
Applications
Metabolism
Smiles
C1CN (CCC1CC (=O) N2CCC (CC2) C3C4=C (CCC5=C3N=CC (=C5) Br) C=C (C=C4Br) Cl) C (=O) N
Molecular Formula
C27H31Br2ClN4O2
Additionnal Information
Lonafarnib (SCH66336) is an orally bioavailable FPTase inhibitor for H-ras, K-ras-4B and N-ras with IC50 of 1.9 nM, 5.2 nM and 2.8 nM in cell-free assays, respectively. Phase 3.
Storage Conditions
2 years -80 in solvent
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