WP1066
Product Specifications
CAS Number
857064-38-1
Target
JAK
Applications
Angiogenesis
Smiles
CC (C1=CC=CC=C1) NC (=O) C (=CC2=NC (=CC=C2) Br) C#N
Molecular Formula
C17H14BrN3O
Additionnal Information
WP1066 is a novel inhibitor of JAK2 and STAT3 with IC50 of 2.30 μM and 2.43 μM in HEL cells; shows activity to JAK2, STAT3, STAT5, and ERK1/2 not JAK1 and JAK3. WP1066 induces apoptosis. Phase 1.
Storage Conditions
2 years -80 in solvent
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