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Sotrastaurin (AEB071)

Product Specifications

CAS Number

425637-18-9

Target

PKC

Applications

Cytoskeletal Signaling

Smiles

CN1CCN (CC1) C2=NC3=CC=CC=C3C (=N2) C4=C (C (=O) NC4=O) C5=CNC6=CC=CC=C65

Molecular Formula

C25H22N6O2

Additionnal Information

Sotrastaurin (AEB071) is a potent and selective pan-PKC inhibitor, mostly for PKCθ with Ki of 0.22 nM in a cell-free assay; inactive to PKCζ. Phase 2.

Storage Conditions

2 years -80 in solvent

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