3-MA (3-Methyladenine)
Product Specifications
CAS Number
5142-23-4
Synonyms
NSC 66389
Target
Autophagy
Applications
Autophagy
Smiles
CN1C=NC (=N) C2=C1N=CN2
Molecular Formula
C6H7N5
Additionnal Information
3-MA (3-Methyladenine) is a selective PI3K inhibitor for Vps34 and PI3Kγ with IC50 of 25 μM and 60 μM in HeLa cells; blocks class I PI3K consistently, whereas suppression of class III PI3K is transient, and also blocks autophagosome formation. Solutions are unstable and should be fresh-prepared.
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