HER2-Inhibitor-1
Product Specifications
CAS Number
937265-83-3
Target
EGFR
Applications
Protein Tyrosine Kinase
Smiles
CC1=C (C=CC (=C1) NC2=NC=NC3=C2C=C (C=C3) C4=CC=C (O4) CNCCS (=O) (=O) C) OC5=CC6=NC=NN6C=C5
Molecular Formula
C29H27N7O4S
Additionnal Information
HER2-Inhibitor-1 is an analog of ARRY-380. ARRY-380 is a potent and selective HER2 inhibitor with IC50 of 8 nM, equipotent against truncated p95-HER2, 500-fold more selective for HER2 versus EGFR.
Storage Conditions
2 years -80 in solvent
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