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GW788388

Product Specifications

CAS Number

452342-67-5

Target

TGF-beta/Smad

Applications

TGF-beta/Smad

Smiles

C1COCCC1NC (=O) C2=CC=C (C=C2) C3=NC=CC (=C3) C4=C (NN=C4) C5=CC=CC=N5

Molecular Formula

C25H23N5O2

Additionnal Information

GW788388 is a potent and selective inhibitor of ALK5 with IC50 of 18 nM in a cell-free assay, also inhibits TGF-β type II receptor and activin type II receptor activities, but does not inhibit BMP type II receptor.

Storage Conditions

2 years -80 in solvent

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