AZ 3146
Product Specifications
CAS Number
1124329-14-1
Target
MPS1
Applications
Cytoskeletal Signaling
Smiles
CN1CCC (CC1) OC2=CC (=C (C=C2) NC3=NC=C4C (=N3) N (C (=O) N4C) C5CCCC5) OC
Molecular Formula
C24H32N6O3
Additionnal Information
AZ3146 is a selective Mps1 inhibitor with IC50 of ~35 nM, contributes to recruitment of CENP-E (kinesin-related motor protein), less potent to FAK, JNK1, JNK2, and Kit.
Storage Conditions
2 years -80 in solvent
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