AG-1478
Product Specifications
CAS Number
153436-53-4,175178-82-2
Synonyms
Tyrphostin AG-1478, NSC 693255
Target
EGFR
Applications
Protein Tyrosine Kinase
Smiles
COC1=C (C=C2C (=C1) C (=NC=N2) NC3=CC (=CC=C3) Cl) OC
Molecular Formula
C16H14ClN3O2
Additionnal Information
AG-1478 is a selective EGFR inhibitor with IC50 of 3 nM in cell-free assays, almost no activity on HER2-Neu, PDGFR, Trk, Bcr-Abl and InsR. AG-1478 (Tyrphostin AG-1478) inhibits encephalomyocarditis virus (EMCV) and hepatitis c virus (HCV) by targeting phosphatidylinositol 4-kinase IIIα (PI4KA) .
Storage Conditions
2 years -80 in solvent
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