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PH-797804

Product Specifications

CAS Number

586379-66-0

Target

P38 MAPK

Applications

MAPK

Smiles

CC1=C (C=C (C=C1) C (=O) NC) N2C (=CC (=C (C2=O) Br) OCC3=C (C=C (C=C3) F) F) C

Molecular Formula

C22H19BrF2N2O3

Additionnal Information

PH-797804 is a novel pyridinone inhibitor of p38α with IC50 of 26 nM in a cell-free assay; 4-fold more selective versus p38β and does not inhibit JNK2. Phase 2.

Storage Conditions

2 years -80 in solvent

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