AMG-900
Product Specifications
CAS Number
945595-80-2
Target
Aurora Kinase
Applications
Cell Cycle
Smiles
CC1=CSC (=C1) C2=NN=C (C3=CC=CC=C32) NC4=CC=C (C=C4) OC5=C (C=CC=N5) C6=NC (=NC=C6) N
Molecular Formula
C28H21N7OS
Additionnal Information
AMG 900 is a potent and highly selective pan-Aurora kinases inhibitor for Aurora A/B/C with IC50 of 5 nM/4 nM /1 nM. It is >10-fold selective for Aurora kinases than p38α, Tyk2, JNK2, Met and Tie2. Phase 1.
Storage Conditions
2 years -80 in solvent
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