LY411575
Product Specifications
CAS Number
209984-57-6
Target
Notch
Applications
Neuronal Signaling
Smiles
CC (C (=O) NC1C2=CC=CC=C2C3=CC=CC=C3N (C1=O) C) NC (=O) C (C4=CC (=CC (=C4) F) F) O
Molecular Formula
C26H23F2N3O4
Additionnal Information
LY411575 is a potent γ-secretase inhibitor with IC50 of 0.078 nM/0.082 nM (membrane/cell-based), also inhibits Notch cleavage with IC50 of 0.39 nM in APP or NΔE expressing HEK293 cells. LY411575 induces apoptosis.
Storage Conditions
2 years -80 in solvent
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