Geldanamycin
Product Specifications
CAS Number
30562-34-6
Synonyms
NSC 122750
Target
HSP (HSP90)
Applications
Cytoskeletal Signaling
Smiles
CC1CC (C (C (C=C (C (C (C=CC=C (C (=O) NC2=CC (=O) C (=C (C1) C2=O) OC) C) OC) OC (=O) N) C) C) O) OC
Molecular Formula
C29H40N2O9
Additionnal Information
Geldanamycin is a natural existing HSP90 inhibitor with Kd of 1.2 μM, specifically disrupts glucocorticoid receptor (GR) /HSP association. Geldanamycin attenuates virus infection-induced ALI (acute lung injury) /ARDS (acute respiratory distress syndrome) by reducing the host's inflammatory responses.
Storage Conditions
2 years -80 in solvent
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