CHIR-124
Product Specifications
CAS Number
405168-58-3
Target
Chk
Applications
Cell Cycle
Smiles
C1CN2CCC1C (C2) NC3=C (C (=O) NC4=C3C=C (C=C4) Cl) C5=NC6=CC=CC=C6N5
Molecular Formula
C23H22ClN5O
Additionnal Information
CHIR-124 is a novel and potent Chk1 inhibitor with IC50 of 0.3 nM in a cell-free assay. It shows 2,000-fold selectivity against Chk2, 500- to 5,000-fold less activity against CDK2/4 and Cdc2.
Storage Conditions
2 years -80 in solvent
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