PF-562271 Besylate
Product Specifications
CAS Number
939791-38-5
Synonyms
PF-00562271 Besylate
Target
FAK
Applications
Protein Tyrosine Kinase
Smiles
CN (C1=C (C=CC=N1) CNC2=NC (=NC=C2C (F) (F) F) NC3=CC4=C (C=C3) NC (=O) C4) S (=O) (=O) C.C1=CC=C (C=C1) S (=O) (=O) O
Molecular Formula
C21H20F3N7O3S.C6H6O3S
Additionnal Information
PF-562271 Besylate is the benzenesulfonate salt of PF-562271, which is a potent, ATP-competitive, reversible inhibitor of FAK with IC50 of 1.5 nM, ~10-fold less potent for Pyk2 than FAK and >100-fold selectivity against other protein kinases, except for some CDKs. Phase 1.
Storage Conditions
2 years -80 in solvent
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