What is the catalog number for RN-1734?

The catalog number for RN-1734 is S2650-5mg.

What sizes are available for RN-1734?

RN-1734 is available in the following size(s): 5 mg.

RN-1734 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures RN-1734?

RN-1734 is manufactured by Bimake.

What is the estimated delivery time for RN-1734?

Estimated delivery time for RN-1734 is approximately 15 business day(s), depending on your location.

RN-1734

Product Specifications

CAS Number

946387-07-1

Synonyms

TRPV4 Antagonist I

Target

TRP Channel

Applications

Neuronal Signaling

Smiles

CC (C) NCCN (C (C) C) S (=O) (=O) C1=C (C=C (C=C1) Cl) Cl

Molecular Formula

C14H22Cl2N2O2S

Additionnal Information

RN-1734 (TRPV4 Antagonist I) is a selective transient receptor potential vanilloid 4 (TRPV4) antagonist with IC50 of 2.3 μM, 5.9 μM and 3.2 μM for hTRPV4, mTRPV4 and rTRPV4, respectively. RN-1734 alleviates demyelination and inhibits glial activation and the production of tumor necrosis factor α (TNF-α) and interleukin 1β (IL-1β) without altering the number of olig2-positive cells.