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SB 200646

Product Specifications

CAS Number

143797-63-1

Synonyms

SB 200646A

Target

5-HT Receptor

Applications

Neuronal Signaling

Smiles

CN1C=CC2=C1C=CC (=C2) NC (=O) NC3=CN=CC=C3

Molecular Formula

C15H14N4O

Additionnal Information

SB 200646 (SB 200646A) is a potent, selective and oral-active antagonist of 5-HT2B/2C over 5-HT2A receptor with 50 fold selectivity. The pKi for rat 5-HT2C receptor, rat 5-HT2B receptor and rat 5-HT2A receptor are 6.9, 7.5 and 5.2, respectively. SB 200646 has electrophysiological and anxiolytic properties in vivo.

Storage Conditions

3 years -20°C powder

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