1-Naphthyl PP1 (1-NA-PP1)
Product Specifications
CAS Number
221243-82-9
Target
Src
Applications
Protein Tyrosine Kinase
Smiles
CC (C) (C) N1C2=NC=NC (=C2C (=N1) C3=CC=CC4=CC=CC=C43) N
Molecular Formula
C19H19N5
Additionnal Information
1-Naphthyl PP1 (1-NA-PP 1) is a highly selective and potent pan-PKD inhibitor with IC50 of 154.6 nM,133.4 nM and 109.4 nM for PKD1, PKD2 and PKD3, respectively. 1-Naphthyl PP1 is a selective inhibitor of Src family kinases (v-Src, c-Fyn) and the tyrosine kinase c-Abl with IC50 of 1.0 μM, 0.6 μM, 0.6 μM, 18 μM and 22 μM for v-Src, c-Fyn, c-Abl, CDK2 and CAMK II, respectively.
Storage Conditions
3 years -20°C powder
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