Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Rabusertib (LY2603618)

Product Specifications

CAS Number

911222-45-2

Synonyms

IC-83

Target

Chk

Applications

Cell Cycle

Smiles

CC1=CC (=C (C=C1Br) NC (=O) NC2=NC=C (N=C2) C) OCC3CNCCO3

Molecular Formula

C18H22BrN5O3

Additionnal Information

Rabusertib (LY2603618, IC-83) is a highly selective Chk1 inhibitor with potential anti-tumor activity in a cell-free assay. IC50=7 nM, showing approximately 100-fold more potent against Chk1 than against any of the other protein kinases evaluated. Rabusertib (LY2603618) induces cell cycle arrest, DNA damage response and autophagy in cancer cells. Rabusertib (LY2603618) induces bak-dependent apoptosis in AML cell lines.

Storage Conditions

2 years -80 in solvent

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

OSGIN2 Mouse Monoclonal Antibody [Clone ID: OTI7D12]
CF808943 100 µg

OSGIN2 Mouse Monoclonal Antibody [Clone ID: OTI7D12]

Sign In for Pricing
View Details
Aurothioglucose 70%-13C6
TRC-A794792-2MG 2 mg

Aurothioglucose 70%-13C6

Sign In for Pricing
View Details
Pdcd1 Hamster Monoclonal Antibody [Clone ID: J43]
AM31881PU-N 250 µg

Pdcd1 Hamster Monoclonal Antibody [Clone ID: J43]

Sign In for Pricing
View Details
Imidacloprid-urea
TRC-I274985-500MG 500 mg

Imidacloprid-urea

Sign In for Pricing
View Details
GFAP (Astrocyte & Neural Stem Cell Marker) (GFAP/2076), CF488A conjugate, 0.1mg/mL
BNC882076-100 1x 100 µL

GFAP (Astrocyte & Neural Stem Cell Marker) (GFAP/2076), CF488A conjugate, 0.1mg/mL

Sign In for Pricing
View Details
1700034I23Rik Mouse Gene Knockout Kit (CRISPR)
KN500138 1 Kit

1700034I23Rik Mouse Gene Knockout Kit (CRISPR)

Sign In for Pricing
View Details