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Fostamatinib (R788)

Product Specifications

CAS Number

901119-35-5

Target

Syk

Applications

Protein Tyrosine Kinase

Smiles

CC1 (C (=O) N (C2=C (O1) C=CC (=N2) NC3=NC (=NC=C3F) NC4=CC (=C (C (=C4) OC) OC) OC) COP (=O) (O) O) C

Molecular Formula

C23H26FN6O9P

Additionnal Information

Fostamatinib (R788), a prodrug of the active metabolite R406, is a Syk inhibitor with IC50 of 41 nM, strongly inhibits Syk but not Lyn, 5-fold less potent to Flt3. Phase 3.

Storage Conditions

2 years -80 in solvent

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