TAK-733
Product Specifications
CAS Number
1035555-63-5
Target
MEK
Applications
Protein Tyrosine Kinase
Smiles
CN1C2=C (C (=C (C1=O) F) NC3=C (C=C (C=C3) I) F) C (=O) N (C=N2) CC (CO) O
Molecular Formula
C17H15F2IN4O4
Additionnal Information
TAK-733 is a potent and selective MEK allosteric site inhibitor for MEK1 with IC50 of 3.2 nM, inactive to Abl1, AKT3, c-RAF, CamK1, CDK2, c-Met, etc. Phase 1.
Storage Conditions
2 years -80 in solvent
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