Mifepristone

Product Specifications

CAS Number

84371-65-3

Synonyms

C-1073, RU 38486

Target

Estrogen/progestogen Receptor

Applications

Endocrinology & Hormones

Smiles

CC#CC1 (CCC2C1 (CC (C3=C4CCC (=O) C=C4CCC23) C5=CC=C (C=C5) N (C) C) C) O

Molecular Formula

C29H35NO2

Additionnal Information

Mifepristone is a remarkably active antagonist of progesterone receptor and glucocorticoid receptor with IC50 of 0.2 nM and 2.6 nM, respectively. Mifepristone promotes cell autophagy and apoptosis, decreases Bcl-2 level and increases Beclin1 level, accompanied by weakened interaction between Bcl-2 and Beclin1.Mifepristone (RU486) can be used to induce animal models of Spontaneous Abortion.