Imatinib

Product Specifications

CAS Number

152459-95-5

Synonyms

STI571, CGP-57148B

Target

PDGFR

Applications

Protein Tyrosine Kinase

Smiles

CC1=C (C=C (C=C1) NC (=O) C2=CC=C (C=C2) CN3CCN (CC3) C) NC4=NC=CC (=N4) C5=CN=CC=C5

Molecular Formula

C29H31N7O

Additionnal Information

Imatinib is a multi-target inhibitor of tyrosine kinase with inhibition for v-Abl, c-Kit and PDGFR, IC50 values are 0.6 μM, 0.1 μM and 0.1 μM in cell-free or cell-based assays, respectively. Imatinib (STI571) induces autophagy.

Storage Conditions

2 years -80 in solvent

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