Gambogic Acid
Product Specifications
CAS Number
2752-65-0
Synonyms
Guttatic Acid, Guttic Acid, Beta-Guttiferrin
Target
Bcl-2
Applications
Apoptosis
Smiles
CC (=CCCC1 (C=CC2=C (C3=C (C (=C2O1) CC=C (C) C) OC45C6CC (C=C4C3=O) C (=O) C5 (OC6 (C) C) CC=C (C) C (=O) O) O) C) C
Molecular Formula
C38H44O8
Additionnal Information
Gambogic Acid (Guttatic Acid, Guttic Acid, Beta-Guttiferrin) activates caspases with EC50 of 0.78-1.64 μM and competitively inhibits Bcl-XL, Bcl-2, Bcl-W, Bcl-B, Bfl-1 and Mcl-1 with IC50 of 1.47, 1.21, 2.02, 0.66, 1.06 and 0.79 μM, respectively.
Storage Conditions
2 years -80 in solvent
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS6375280-01 0.1 mL
CYC1 (Cytochrome C1, Heme Protein, Mitochondrial, Complex III Subunit 4, Complex III Subunit IV, Cytochrome b-c1 Complex Subunit 4, Ubiquinol-cytochrome-c Reductase Complex Cytochrome C1 Subunit, Cytochrome C-1) (PE)
Sign In for Pricing
View Details 
MBS6375280-02 5x 0.1 mL
CYC1 (Cytochrome C1, Heme Protein, Mitochondrial, Complex III Subunit 4, Complex III Subunit IV, Cytochrome b-c1 Complex Subunit 4, Ubiquinol-cytochrome-c Reductase Complex Cytochrome C1 Subunit, Cytochrome C-1) (PE)
Sign In for Pricing
View Details 
MBS6183464-01 0.1 mL
TOPBP1 (Topoisomerase (DNA) II Binding Protein 1, TOP2BP1) (HRP)
Sign In for Pricing
View Details