PF-04457845
Product Specifications
CAS Number
1020315-31-4
Synonyms
PF-4457845
Target
FAAH
Applications
Neuronal Signaling
Smiles
C1CN (CCC1=CC2=CC (=CC=C2) OC3=NC=C (C=C3) C (F) (F) F) C (=O) NC4=NN=CC=C4
Molecular Formula
C23H20F3N5O2
Additionnal Information
PF-04457845 (PF-4457845) is a potent, favorable selective inhibitor of Fatty acid amide hydrolase (FAAH) with IC50 of 7.2 nM and 7.4 nM for hFAAH and rFAAH, respectively. PF-04457845 covalently modifies the active-site serine nucleophile of FAAH with exquisite selectivity relative to other members of the serine hydrolase superfamily.
Storage Conditions
3 years -20°C powder
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