Cryptotanshinone (Tanshinone C)
Product Specifications
CAS Number
35825-57-1
Target
STAT
Applications
Apoptosis
Molecular Formula
C19H20O3
Additionnal Information
Cryptotanshinone (Tanshinone C) is a STAT3 inhibitor with IC50 of 4.6 μM in a cell-free assay, strongly inhibits phosphorylation of STAT3 Tyr705, with a small effect on STAT3 Ser727, but none against STAT1 nor STAT5. Cryptotanshinone induces ROS-dependent autophagy and mitochondria-mediated apoptosis.
Storage Conditions
2 years -80 in solvent
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