Momelotinib (CYT387)
Product Specifications
CAS Number
1056634-68-4
Synonyms
LM-1149 , CYT11387
Target
JAK
Applications
Angiogenesis
Smiles
C1COCCN1C2=CC=C (C=C2) NC3=NC=CC (=N3) C4=CC=C (C=C4) C (=O) NCC#N
Molecular Formula
C23H22N6O2
Additionnal Information
Momelotinib (CYT387, LM-1149 , CYT11387) is an ATP-competitive inhibitor of JAK1/JAK2 with IC50 of 11 nM/18 nM, ~10-fold selectivity versus JAK3. Momelotinib (CYT387) induces apoptosis and autophagy. Phase 3.
Storage Conditions
3 years -20°C (in the dark) powder
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