Torkinib (PP242)
Product Specifications
CAS Number
1092351-67-1
Target
Autophagy
Applications
Autophagy
Smiles
CC (C) N1C2=NC=NC (=C2C (=N1) C3=CC4=C (N3) C=CC (=C4) O) N
Molecular Formula
C16H16N6O
Additionnal Information
Torkinib (PP242) is a selective mTOR inhibitor with IC50 of 8 nM in cell-free assays; targets both mTOR complexes with >10- and 100-fold selectivity for mTOR than PI3Kδ or PI3Kα/β/γ, respectively. Torkinib (PP242) induces mitophagy and apoptosis.
Storage Conditions
2 years -80 in solvent
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