DAPT

Product Specifications

CAS Number

208255-80-5

Synonyms

GSI-IX, LY-374973

Target

Beta Amyloid

Applications

Neuronal Signaling

Smiles

CC (C (=O) NC (C1=CC=CC=C1) C (=O) OC (C) (C) C) NC (=O) CC2=CC (=CC (=C2) F) F

Molecular Formula

C23H26F2N2O4

Additionnal Information

DAPT is a novel γ-secretase inhibitor, which inhibits Aβ production with IC50 of 20 nM in HEK 293 cells. DAPT enhances the apoptosis of human tongue carcinoma cells and regulates autophagy.

Storage Conditions

2 years -80 in solvent

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