Avasimibe

Product Specifications

CAS Number

166518-60-1

Synonyms

CI-1011, PD-148515

Target

P450 (e.g. CYP17)

Applications

Metabolism

Smiles

CC (C) C1=C (C (=CC=C1) C (C) C) OS (=O) (=O) NC (=O) CC2=C (C=C (C=C2C (C) C) C (C) C) C (C) C

Molecular Formula

C29H43NO4S

Additionnal Information

Avasimibe inhibits ACAT with IC50 of 3.3 μM, also inhibits human P450 isoenzymes CYP2C9, CYP1A2 and CYP2C19 with IC50 of 2.9 μM, 13.9 μM and 26.5 μM, respectively.

Storage Conditions

2 years -80 in solvent

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