Avasimibe
Product Specifications
CAS Number
166518-60-1
Synonyms
CI-1011, PD-148515
Target
P450 (e.g. CYP17)
Applications
Metabolism
Smiles
CC (C) C1=C (C (=CC=C1) C (C) C) OS (=O) (=O) NC (=O) CC2=C (C=C (C=C2C (C) C) C (C) C) C (C) C
Molecular Formula
C29H43NO4S
Additionnal Information
Avasimibe inhibits ACAT with IC50 of 3.3 μM, also inhibits human P450 isoenzymes CYP2C9, CYP1A2 and CYP2C19 with IC50 of 2.9 μM, 13.9 μM and 26.5 μM, respectively.
Storage Conditions
2 years -80 in solvent
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