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AZD1480

Product Specifications

CAS Number

935666-88-9

Target

JAK

Applications

Angiogenesis

Smiles

CC1=CC (=NN1) NC2=NC (=NC=C2Cl) NC (C) C3=NC=C (C=N3) F

Molecular Formula

C14H14ClFN8

Additionnal Information

AZD1480 is a novel ATP-competitive JAK2 inhibitor with IC50 of 0.26 nM in a cell-free assay, selectivity against JAK3 and Tyk2, and to a smaller extent against JAK1. Phase 1.

Storage Conditions

2 years -80 in solvent

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