Sonidegib
Product Specifications
CAS Number
956697-53-3
Synonyms
NVP-LDE225, Erismodegib
Target
Hedgehog/Smoothened
Applications
Stem Cells & Wnt
Smiles
CC1CN (CC (O1) C) C2=NC=C (C=C2) NC (=O) C3=CC=CC (=C3C) C4=CC=C (C=C4) OC (F) (F) F
Molecular Formula
C26H26F3N3O3
Additionnal Information
Sonidegib is a Smoothened (Smo) antagonist, inhibiting Hedgehog (Hh) signaling with IC50 of 1.3 nM (mouse) and 2.5 nM (human) in cell-free assays, respectively. Phase 3.
Storage Conditions
2 years -80 in solvent
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