Licofelone (ML3000)
Product Specifications
CAS Number
156897-06-2
Target
COX
Applications
Neuronal Signaling
Smiles
CC1 (CC2=C (C (=C (N2C1) CC (=O) O) C3=CC=C (C=C3) Cl) C4=CC=CC=C4) C
Molecular Formula
C23H22ClNO2
Additionnal Information
Licofelone (ML3000, Compound 3e) is a dual inhibitor of COX and 5-lipoxygenase (5-LOX) with IC50 of 0.21 μM and 0.18 μM, respectively. Licofelone induces apoptosis, and decreases the production of proinflammatory leukotrienes and prostaglandins. Licofelone is considered as a treatment for osteoarthritis.
Storage Conditions
2 years -80 in solvent
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